2023-06-05 15:08:06
DNTH: Atherosclerosis is quite dangerous disease and occurs for a long time. In the early stages, patients often have no symptoms, only when the plaque develops, causing the artery lumen to narrow significantly, reducing blood flow to the organs. Only then will new symptoms appear.
"Coenzyme Q10 contained in the CoQ10 pill is evaluated as a very high antioxidant, existing in body tissue cells. This is a particularly useful and important nutrient for the cardiovascular system, has a controlling effect on the cardiovascular system. Control and minimize cholesterol levels in the blood, stabilize heart rate and regulate blood pressure.CoQ10 helps keep blood vessel walls soft and elastic, supports blood circulation more smoothly, and limits the formation of blood vessels. the walls of blood clots and plaque, thereby promoting smooth blood circulation in the body, limiting stroke and "myocardial infarction"
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Atherosclerosis can occur in all arteries such as coronary, carotid, cerebral arteries, aorta and its branches as well as great extremity arteries. It is the leading cause of morbidity and mortality in developed countries. In 2019, cardiovascular diseases, mainly coronary and cerebral atherosclerosis, caused nearly 18 million deaths worldwide, accounting for over 30% of all deaths.
Atherosclerosis often has no symptoms in the first decades, when plaque forms. Symptoms appear when blood vessels have been damaged, which impedes blood flow. Transient ischemic symptoms such as angina on exertion, transient ischemic attack causing headache, pain in the extremities at rest... that sign appears when the atherosclerotic plaque grows and causes narrowing larger 70 % vascular lumen.
Pathological condition due to atherosclerosis in some functional organs
- Coronary atherosclerosis when blood flow to the heart is not enough, will cause symptoms of angina due to myocardial ischemia, palpitations, congestion, liver edema, increased oxygen deficiency in the heart ...
- Atherosclerosis of the blood supply to the brain, there may be signs such as numbness in the limbs or a feeling of weakness and powerlessness; difficulty speaking or stuttering; temporary loss of vision in one eye or drooping facial muscles. Signs of a transient ischemic attack, if not treated promptly, can turn into a cerebrovascular accident.
- Atherosclerosis in the limbs, patients will have symptoms of peripheral artery disease, appear signs like cramping pain, pain when moving or resting.
- Atherosclerosis in the kidney, the patient may have high blood pressure or kidney failure.
Illustration of blood vessels when atherosclerotic
"Coenzyme Q10 (CoQ10) is a natural compound, found in the mitochondria of plant and animal cells. In the human body, CoQ10 is found in almost all tissues, most notably in the heart, kidney, liver, pancreas, and colon tissues. Mitochondria are known as an energy factory for our body, each cell has about a few thousand mitochondria. The task of this factory is to carry out the process of cellular respiration to metabolize nutrients. substances from the food that are absorbed, converted into an energy source. Mitochondria produce up to 90% of the energy that our bodies need to function."
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Oxidation is what causes cell damage and affects their inherent functions. If your body can't fight oxidation effectively, or lacks the energy for the organs in your body to function properly, the structure of your cells is at risk of damage. for the development of atherosclerotic disease.
Some causes of atherosclerosis
Dyslipidemia: Dyslipidemia (high total cholesterol, high LDL, low HDL), hypertension and diabetes promote atherosclerosis;
Hypertension can lead to vasculitis through mechanisms mediated by angiotensin II. Angiotensin II stimulates endothelial cells, vascular smooth muscle cells and macrophages to produce atherogenic mediators;
Diabetes will form glycans, which cause the production of pro-inflammatory cytokines from endothelial cells. Oxidants and oxygen-containing free radicals generated in diabetes directly damage the endothelium and promote atherosclerosis;
Chronic kidney disease promotes the development of fibromyalgia, hypertension and insulin resistance; reduce apolipoprotein AI; increased lipoproteins, promoting atherosclerosis;
Cigarette smoke contains nicotin and chemicals that are toxic to the vascular endothelium, including passive smoking, which increases platelet reactivity. High plasma fibrinogen and hematocrit concentrations increase blood viscosity. Smoking increases LDL and lowers HDL, promoting blood vessel constriction. This is especially dangerous on arteries that have been narrowed by previous atherosclerosis;
In addition, a number of other causes also cause atherosclerosis such as obesity, family history of atherosclerosis, sedentary, not regularly playing sports ...
Support the treatment of atherosclerosis
Lifestyle changes including dietary changes, smoking cessation, regular sports activity; Use drugs as indicated in the treatment of dyslipidemia, antiplatelet, hypertension and diabetes. The above lifestyle changes and medications can improve endothelial function and reduce the risk of atherosclerotic death even when serum cholesterol is normal or slightly elevated.
Increased use of fiber reduces cholesterol, is beneficial for glucose balance and insulin levels. Regular consumption of soluble fiber such as oat bran, beans, and soy products every day can lower LDL. Insoluble fibers, such as cellulose and lignin, do not affect cholesterol but may offer other benefits such as a reduced risk of colon cancer by stimulating bowel movements, or by reducing the duration of exposure to carcinogens. letter in food. However, too much fiber affects the absorption of certain minerals and vitamins.
Alcohol use increases HDL, helps reduce the risk of thrombosis, antioxidant and anti-inflammatory is not clear. These effects appear to be the same for alcohol, beer, and spirits and appear when consumed in moderation. However, regular alcohol use at higher levels can cause other health problems.
"There is little evidence for the anti-atherosclerotic role of vitamin, phytochemical and trace mineral supplements, with the only exception being fish oil. Levels of coenzyme Q10 (CoQ10) are required for basal cell activity, which tends to decrease with age and may be low in some patients with cardiovascular and other chronic conditions.As a result, CoQ10 supplements have been used or recommended for use. tends to increase in developed countries.
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